1 A Field Guide to Lies Critical Thinking in the Information Age - Explains common misuses of statistics and misrepresentation of probability. Use common sense as the first line of defense. This impacts advertising, criminal trials (what is the likelihood that the defendant is guilty based on the blood found at the scene vs whats the possibility that any other individual is guilty based on the blood found at the scene). - Post hoc ergo propter hoc- After this, therefore because of this. Because this event followed another event, the subsequent event must have been caused by the first event. We link events that might be temporarily related but aren't actually cause and effect. - Likelihood of two unrelated events both happening= probability of event 1 x probability of event 2→ lower than the probability of each event independently. Likelihood of flipping one head on a coin followed by flipping another head. - Likelihood of two related events- for example, the likelihood of freezing weather tonight and tomorrow night→ higher given the occurrence of freezing weather the first night. - Vaccines lead to autism? People look at the increased percentage of autism diagnoses. Autism was more frequently diagnosed because it became more understood. Autism is commonly diagnosed between 18-24 months and the MMR vaccine is given around 12 months. - Was 9/11 an inside job? Why did the towers collapse vertically? Easy to overwhelm with questions and theories designed to cast doubt on the events. But structural engineers never found anything suspicious about it. - Breast cancer. Pretest probability- occurrence in the population. 1/8 women develop BrCA. Mammograms can over-call diagnoses (false positive). - Positive test + confirmed diagnosis= true positive - Negative test + confirmed absence of diagnosis= true negative - Positive test + confirmed absence of diagnosis= false positive (low FP= high specificity) - Negative test + confirmed diagnosis= false negative (low FN= high sensitivity) Previous Next

< Back ICU Rounding: How I Do It The ICU can be intimidating. Critically ill patients are often surrounded by machines (ventilators, dialysis, etc) and IV poles, with multiple lines and catheters extending from their face, chest, abdomen, neck, and groin. A standardized approach can help the team synthesize and interpret all the subjective and objective data to establish a diagnosis and devise a treatment plan for these complex patients. Rounding in the ICU is different from rounding on floor patients. Floor patients are typically presented in a problem-based format- they are likely to have a short list of active issues being addressed, often just one diagnosis (cholecystitis, bowel obstruction, colon cancer status-post colectomy). Patients can certainly have co-morbidities, such as diabetes and hypertension, but they are usually relatively straightforward. Presentations are briefer than ICU presentations, and largely focus on the acute surgical diagnosis. Here is an example of a surgical floor patient. 32 year old female, hospital day 2 following laparotomy for small bowel obstruction. Her pain is controlled with oral analgesics with minimal prn requirements. She is hungry and passing flatus. She is using her incentive spirometry and ambulating. She has had minimal output in her nasogastric tube. Staples are intact along her midline laparotomy incision with no surrounding erythema and appropriate peri-incisional tenderness. Labs are only remarkable for some mild hypokalemia with K 3.4. She is voiding spontaneously with adequate urine output. Plan to replete potassium, remove NGT and advance diet. In contrast, ICU patients are fragile with more physiologic derangements that threaten homeostasis. Critical illness can profoundly impact multiple organ systems and the interdependence of organ systems adds another layer of complexity. Patients can be presented in a problem-based format, like floor patients, or a system-based format. There are pros and cons to each. As mentioned, a problem-based format addresses each diagnosis (for example- cholecystitis, bowel obstruction, heart failure, pneumonia, ileus). In contrast, a system-based format addresses each organ system (for example- cardiac, pulmonary, renal, neurologic). Problem-based might seem easier on first glance, but one downside in the ICU setting is the risk of overlooking organ systems without a discrete disease process. One downside of the system-based format is the categorization of one diagnosis to various organ systems. For example, ventilator-associated pneumonia is related to the pulmonary system but overlaps with infectious disease. However, the system-based format is comprehensive and thorough, which helps ensure that all physiologic processes are considered. One advantage of the system-based format is it’s adaptability to less complex patients. While it’s challenging to apply floor round formatting to the ICU setting, once you understand how to utilize the ICU system-based model, you can use it to briefly review non-ICU patients to ensure that you don’t forget something. For a young male with cholecystitis, you don’t need to report GCS, medication infusion rates, ventilator settings, insulin requirements, etc. But the systems are still pertinent- address pain (neuro), ensure normal vitals (cardiac) and use of incentive spirometer (pulmonary), check oral intake, assess return of bowel function and examine wounds (GI), inquire about adequate urination and review BMP (renal), ensure no fever, review CBC (heme and ID), and ensure ambulation/ SCDs (prophylaxis). ICU care is a team endeavor, requiring the integration of nursing, respiratory therapy (RT), dieticians, pharmacists, physical therapy and other team members to provide comprehensive care. ICUs must implement a system to integrate care plans between all team members. This can occur in different formats, either with “prerounds” (brief discussion with multidisciplinary team about each patient before formal rounds) or with multidisciplinary rounds (team members present their key data points/ plans in a structured format). One example of multi-disciplinary rounds (abbreviated): resident reports one-liner (see example below); nurse reports their assessments (pain/ sedation scores, delirium assessment, etc); RT reports current ventilator settings, results of spontaneous breathing trials and respiratory treatments; the resident then presents the patient as below. Order of Presentation during Rounds 1. Brief one-liner [presented by the resident, APP or student caring for the patient]. See below. 2. Bedside nurse- report on sedation, pain, infusion rates, etc 3. Respiratory therapy- report on ventilator settings, respiratory interventions, etc 4. Formal patient presentation [presented by the resident, APP or student caring for the patient]. See below. 5. Pharmacist- review of medications, including potential dose adjustments, antibiotic tailoring, etc 6. Attending 7. FAST-HUG- ensure that key aspects of care are addressed (feeding, analgesia, sedation, thromboprophylaxis, head of bed elevated, ulcer prophylaxis, glycemic control) 8. Readback- nurse briefly summarizes the key goals of the day One-liner: brief patient history, acute overnight events. Example: 32 year old male, POD 7 exploratory laparotomy following motor vehicle collision, remains intubated for VAP. Formal Patient Presentation [Systems Based] Neurologic (Neuro) Diagnosis: Exam/ objective data. GCS, reflexes, pupils. ICP monitor. Medication: continuous infusions, requirements of prn analgesics Plan: Neuro- patient remains intubated and sedated, GCS 11T off sedation, currently on Fentanyl @ 100 mcg/ hr and propofol @ 20. Minimal requirements of prn analgesics. We will wean fentanyl infusion and use enteral multi-modal analgesia. Cardiac Diagnosis: Exam/ objective data. Vitals: describe the trend, know when outliers occurred (for example, an isolated heart rate (HR) of 130 during a procedure at noon the previous day is different from a sustained HR of 130s). If patient has any invasive monitoring, such as arterial pressure waveform analysis (FloTrac, Vigileo), pulmonary artery catheter or central line, include these as well. Medication: Plan: Cardiac: HR 90s-100s, Flotrac shows normal SVV. On norepinephrine, requirement is currently down to only 2 from a max of 10 yesterday, MAP goal of >65. Continue to wean norepinephrine. Remove arterial line once off norepinephrine for 12 hours. Pulmonary (Pulm) Diagnosis: Exam/ objective data: intubated, secretions, breath sounds, breathing pattern. Ventilator settings. Labs: ABG if performed. Imaging: note findings, and describe how it’s changed relative to prior imaging Medication: Plan: Example: Pulm- pt remains intubated, current ventilator settings. CXR still shows bilateral fluffy infiltrates. *on antibiotics day x of x for VAP, CXR worsening/ stable, secretions improving. Then, later: ID- patient is on antibiotics day x of x for UTI, and day x of x for VAP. Gastrointestinal (GI)/ Nutrition Diagnosis: Exam/ objective data: abdominal wounds, drains, stool management system, bowel function, nutrition. Medication: bowel regimen Plan: GI- patient started on tube feeds two days ago, but he’s having minimal stool output. Abdomen is distended and tympanitic. We held feeds this morning and have an abdominal plain film pending. Renal/ Fluids/ Electrolytes (Renal) Diagnosis: Exam/ objective data. IV fluids. Intake/ output. BMP. Medication: Plan: Renal- foley in place with good urine output, I/O 3.2L/2.9L. No continuous IV fluids. Electrolytes within normal limits. Hematologic (Heme) Diagnosis: Exam/ objective data. Labs: Hgb, Plt. Transfusion. Medication: Plan: Heme- stable mild anemia, checking CBC every Monday/ Wednesday/ Friday. Infectious Disease (ID) Diagnosis: Exam/ objective data. Labs: WBC, neutrophils. Culture results (sample source, date, results). Medication: current antimicrobials. Plan: ID- patient is on antibiotics day 2/5 for UTI, and day 2/5 for VAP. He has remained afebrile for the last 48 hrs. His WBC is downtrending. No pending cultures. Endocrine (Endo) Diagnosis: Exam/ objective data. Labs: glucose trend, insulin requirements Medication: Plan: Endo- stress hyperglycemia, glucose range from 210-240. Currently on SSI with 24 hr requirement of 22U. Increase to more aggressive sliding scale, but holding off adding scheduled/ basal insulin while adjusting his enteral nutrition. Prophylaxis/ Lines and Tubes GI prophylaxis DVT prophylaxis Location/ date of invasive lines and tubes Patient is on IV PPI for ulcer prophylaxis, on enoxaparin BID. PICC RUE, day 10. Foley, day 5. Helpful hints: - Be succinct and synthesize the data. Have all the information available if asked, but don’t report every single bit of data. - Some problems can be relevant to multiple systems. For example, ventilator-associated pneumonia is related to the pulmonary system but overlaps with infectious disease. You can pick one system to discuss it, but you can also briefly mention it in the other relevant system. For example: Pulmonary- patient remains intubated, on antibiotics day x of x for VAP, CXR worsening/ stable, secretions improving. Then, later: ID- patient is on antibiotics day x of x for UTI, and day x of x for VAP. - If the patient’s BMP is normal, you can state that instead of reading every value. If there is one lab value that is abnormal but the remainder is normal, you can say “normal except for [elevated potassium of 5.5]” - Be thoughtful about ordering labs and imaging. Daily CXR purely because a patient is intubated for a bad TBI is not necessarily helpful. Even if the patient is being treated for pneumonia, daily CXR is unlikely to change your management unless there is a clinical change. CXR is appropriate if there are specific interventions that were performed or if the patient has a clinical deterioration- for example, following placement of chest tube for pleural effusion, following 24 hours of aggressive diuresis, for evaluation of acute dyspnea/ hypoxia. - Don’t repeat information presented by other team members- if the nurse has already provided infusion rates or RT has already provided ventilator settings, just move through the next part of the presentation. ICU Rounds .pdf Download PDF • 46KB A-F Bundle .pdf Download PDF • 33KB Previous Next

< Back Anemia...pending Anemia Previous Next

The emotional stress and challenges of ACS I could never do your job < Back The emotional stress and challenges of ACS René Leriche, “Every surgeon carries within himself a small cemetery, where from time to time he goes to pray—a place of bitterness and regret, where he must look for an explanation for his failures.” Acute Care Surgery is not an easy profession. My time as a surgical critical care fellow challenged me in ways I never predicted. The challenges of this field are numerous, although not all are unique to acute care surgery. Historically, trauma surgeons worked long hours (with the associated sleep disruptions), unpredictable workloads managing a mixture of high acuity critically-ill and injured patients, high patient mortality rates, and frequent exposure to horrifically injured patients.(1) Despite my intense desire to pursue this, I didn't truly grasp the depth of the emotional toll I would face. I am incredibly grateful to the mentors who guided me during my fellowship. I have told plenty of family members about the death of their loved one. There is a palpable difference between the interaction with a family of a patient you never knew- someone who came in unresponsive or someone who died shortly after arrival. It’s tragic, without a doubt, and it’s never easy to tell a family about this unexpected loss. But managing patients in the ICU, you have the opportunity to talk to them, to learn about them as real people, to meet their family. There are a few specific patients and family conversations I will never forget. After a busy week during the winter holidays, I was already emotionally drained. Friday morning, I sat in a large room full of family members and had to break the news that their loved one had become significantly sicker overnight. Unfortunately, he continued to deteriorate, and the following day, I had to tell them there was nothing else we could do. From my viewpoint, all human life is valuable. Sometimes it seems incredibly hopeless, which leaves us feeling helpless. It took me a while to gather myself for the second conversation with that same large family. I confided in my attending that I didn't think I could get through the conversation without tears. Thankfully, she gave me the gift of acceptance- she told me that I had established rapport with the family, and it was okay to cry. She also reminded me that I wouldn't have to give a long speech because they would already know that it wasn't good news. I am grateful for the opportunities I had to witness intense conversations between senior trauma surgeons and various critical care physicians and patients and families. I learned lots of critical care and patient management, the principles of managing multiple critically ill patients, and advanced operative techniques of trauma and emergency general surgery. But I am most grateful for the "art of medicine" that I learned from my mentors, which can't be taught in a textbook. Learning how to deliver bad news and help families navigate the difficult decision-making process are vital skills in this profession. This is a challenging specialty. It demands expertise in multiple clinical disciplines, the skill to manage multiple critically ill patients and the ability to balance contradictory needs of competing organ dysfunctions in one patient. Thankfully, with a good team of senior surgeons, you can navigate the nuances while training to practice this honorable profession. 1. The Committee to Develop the Reorganized Specialty of Trauma, Surgical Critical Care, and Emergency Surgery. Acute Care Surgery: Trauma, Critical Care, and Emergency Surgery. J Trauma. 2005;58:614 –616. Previous Next

< Back Fever...pending Evaluation of Fever Previous Next

< Back Chunky Tomato Bisque Ingredients 6 celery ribs, chopped 1 large onion, chopped 1 medium sweet red pepper, chopped 1/4 cup butter, cubed 3 cans (14.5 oz each) diced tomatoes, undrained 1 tablespoon tomato paste 3/4 cup loosely packed basil leaves, coarsely chopped 3 teaspoons sugar 2 teaspoons salt 1/2 teaspoon pepper 1-1/2 cups heavy whipping cream Instructions 1. In a large saucepan, sauté the celery, onion and red pepper in butter for 5-6 minutes or until tender. Add tomatoes and tomato paste. Bring to a boil. Reduce heat; cover and simmer for 40 minutes. 2. Remove from the heat. Stir in the basil, sugar, salt and pepper; cool slightly. 3. Transfer half of the soup mixture to a blender. While processing, gradually add cream; process until pureed. Return to the pan; heat through (do not boil). The vegetables sautéing Previous After blending Dinner is served! Next

< Back Definitions Common Abbreviations ACS- Acute care surgery. Field of surgery that encompasses trauma, emergency general surgery and surgical critical care. APP- advanced practice provider. Includes physician assistants (PA) and nurse practitioners (NP). ICU- intensive care unit. Higher-acuity (sicker) patients requiring closer monitoring (continuous evaluation of vital signs), more invasive or more frequent interventions (mechanical ventilation, multiple cardiac medication infusions). CRNA- certified registered nurse anesthetist. CRRT- continuous renal replacement therapy. EGS- Emergency General Surgery. GCS- Glasgow Coma Scale. IV- intravenous. MCC- motorcycle crash/ collision. MVC- motor vehicle crash/ collision. SCC- surgical critical care. Common Personnel - Attending physician- most senior physician caring for a patient. - Bedside nurse- the nurse who provides the direct patient care, including assessing a patient's current clinical status, providing medications, interact with other teams that see the patient such as physical therapy or the wound care team, placing urinary catheters and monitoring urine output, communicating with the patient's physician team, providing patient education. - Chief Resident- resident in their final year of residency training. - Fellow- a physician that has completed preliminary training and undertakes advanced training in a subspecialty. Typically follows residency graduation, although Surgical Critical Care can be completed prior to graduating from surgical residency. - Intern- a physician in their first year of residency training following medical school graduation. Common Procedures - Arterial line placement- similar to an IV, this is a skinny catheter, but instead of being in a vein, it’s placed in an artery. This allows continuous monitoring of blood pressure and allows repeat labs, specifically arterial blood gas to assess respiratory status. - Bronchoscopy- use of a small camera (think of a really skinny colonoscope) to examine the airways of the lungs, take a specimen for culture or remove an obstruction. - Central line placement- placement of a large catheter into a large vein in the neck, under the clavicle (collarbone), or in the groin. The purpose is similar to an IV (intravenous) line, which is commonly placed to provide medication, fluids, or draw blood. A central line is larger- more drips can be connected to it, it can be kept in place longer than a peripheral IV, and it can allow delivery of special medications. - Intubation- placement of a plastic breathing tube (endotracheal tube) through a patients mouth, into their trachea (airway). Patients receive sedation medication and paralytic medication (medication to prevent muscle movement. This is commonly used for patients who are unconscious or are having breathing difficulties. It is also commonly used while patients are undergoing surgery - Laparotomy- vertical incision on the abdomen to allow examination of the organs in the abdomen. Also known as an “exploratory laparotomy” or “ex lap”. - Ostomy creation- in the unplanned setting, patients who undergo emergent surgery for trauma or bowel ischemia/ perforation, a segment of the bowel might be removed, reconnected or repaired. These patients are at a higher risk for their bowel connection or repair to fall apart (known as an anastomotic leak). To prevent this, sometimes it is safer to divert the stool toward an opening in the skin to allow stool to pass outside into a bag, instead of moving into the intestine that was repaired/ reconnected. - Ostomy reversal- reconnection of the bowel after a patient has recovery from emergency surgery. The bowel is reconnected (so the patient will now pass stool normally) and the skin opening is closed. - Percutaneous endoscopic gastrostomy tube (PEG)- creation of a connection directly through the anterior abdominal wall into the stomach to allow feeding without requiring a tube in the patient’s nose. - Thoracotomy- incision on the chest to allow access to the organs in the chest (heart, lungs, esophagus). - Tracheostomy- creation of a connection directly from the front of the neck to the trachea (airway). A short curved tube is placed in the open, and the endotracheal tube (breathing tube) is removed from the mouth. Common definitions - Rounds- the process of evaluating and examining patients currently in the hospital. Previous Next

The person you know her as isn’t there anymore Goals of Care < Back The person you know her as isn’t there anymore I have used those words on countless occasions while explaining severe/ non-survivable brain injury to patient's families. There are many phrases that providers use to describe end-of-life care. Palliative care. Palliative extubation. Withdrawal of care. Withholding of care.(1) Words are powerful, and conversations about the death of a loved one are remembered well into the future. What they hear can significantly impact their perception of how you are caring for their family or friend. Phrases such as “withdrawing care” can signal that the medical team is giving up and sticking their mother or child or best friend in a dark corner to die a miserable death. We aren’t withdrawing care- in reality, we are continuing to provide maximal patient care, following their wishes. Just because the result is death doesn’t mean we aren’t caring. Death isn’t pretty, and we shouldn’t pretend that we can eliminate the family's pain. But our approach to providing a peaceful dignified death with minimal pain and distress and anxiety can ease some of the family's distress. During my year of dedicated ICU training, I have guided countless families through the decision-making process of end of life care and several conversations will be permanently etched in my memory. I am grateful that I was able to witness and learn from some incredibly experienced and compassionate critical care physicians. While I can’t completely pull back the curtain on the details of these conversations or the specifics of treatment at the end of life, I will share some of the wisdom I gleaned. The patient is already being actively cared for when we have these conversations. Pain and anxiety are treated, bony prominences positioned and patients are turned frequently to prevent pressure wounds. The focus of the conversation is directed at relieving the emotional suffering and distress of the family and friends. Every conversation is different, and empathy and tact are paramount. Also, allowing time for people to express their thoughts is important. It allows them to unload what they are struggling with and also allows the team to tailor the discussion to address their specific concerns. Loved ones present a wide spectrum of emotions. Recognizing and validating these feelings is one way to reassure people that what they are experiencing is not abnormal. It's also a very important step in assessing their understanding of the gravity of the current situation, as well as developing a sense of what their wishes would be (ie mom was very independent and would never want to live like this, my husband writes and teaches, and he wouldn't want to exist if he can't interact in a meaningful way). Some struggle with guilt about unresolved disputes. Others struggle with the crushing sadness of unrealized dreams for their child. But one emotion and concern that is almost universal is guilt about deciding to proceed with comfort care. One such interaction that I will never forget was about the children who were wrestling with the thought of giving up and letting go of their mother who had a devastating brain injury after a car accident. Their respect and love for their mother made it challenging to reconcile with the reality that she wasn’t ever going to be the same person. They talked about how strong and independent she was, and how she would never want to exist in a state of complete dependence. As I sat quietly listening, I heard the words of one of my mentors in my head…”You are showing your love for your mother. This is a gift that you can give her.” We will never erase their feelings, but we can provide reassurance that they aren't inflicting pain and suffering on their family, but they are actually respecting their wishes not to live in this condition. One of the phrases I adopted during my training was “The person you know her (him) as isn’t there anymore.” Seeing flickers of movement, watching their chest rise and fall, and feeling the warmth of their skin can all give hope, that maybe with time and aggressive care, their husband will return to them, their child will wake up and smile at them. The invisible truth of a devastating injury often hides the reality. It is our responsibility and privilege to guide these families through what is likely to be one of the most heart-wrenching moments of their life and to show compassion in our conversation and our care for their loved one. We aren't withdrawing care- we care for our patients until they die, but our goals of care should shift to align with their wishes. Previous Next

< Back Frequently Asked Questions What level of schooling/ education/ training is required to be an Acute Care Surgeon? - Traditionally, 4 years of undergraduate education and 4 years of medical school. - Surgery residency, typically 5 clinical years, sometimes an optional or mandatory research year (or more). - Following residency, there is a written exam that qualifies you to take the oral boards. Passing oral boards equates to Board Certification in General Surgery. - Fellowship- one year mandatory for surgical critical care certification. Acute Care Surgery requires two years of training. - Following a surgical critical care fellowship (after completing one year SCC fellowship, or after the critical care year of your ACS fellowship), there is a written exam requirement for Board Certification in Surgical Critical Care. What is the best part of your job? Relieving patients suffering. We meet people on what is probably the worst day of their life. Whether it’s a traumatic injury or a surgical emergency, our patients arrive in crisis. We can minimize or alleviate their suffering. What is the worst part of your job? Having to tell families that their loved one died. We meet people on what is probably the worst day of their life. We have to quickly establish rapport and tell them terrible news. We ask strangers to trust that we did everything to keep their child, spouse, or parent alive. Previous Next

< Back Stomach Ulcers UpToDate Patient Information Patient education: Peptic ulcer disease (Beyond the Basics) Patient education: Helicobacter pylori infection and treatment (Beyond the Basics) Patient education: Upper endoscopy (Beyond the Basics) Patient Information from Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Upper Endoscopy Previous Next

< Back Anal Fissure What is an anal fissure? Patient information: Anal fissure [American College of Colon and Rectal Surgeons] Patient education: Anal fissure (Beyond the Basics) [UpToDate] Trauma from hard stool (constipation) creates a tear in the anoderm distal to the dentate line. Pain leads to internal sphincter spasm, setting up a vicious cycle! Symptoms- severe pain during and immediately following a bowel movement ("like pooping glass", "passing a razor blade"), blood on toilet paper with wiping. This often leads to fear of having bowel movements. Pain leads to muscle spasm→ higher pressure→ vicious cycle. Diagnosis- classic history is almost enough, but pain with effacement of the buttocks and visualization of a tear in the anoderm confirms. Don’t torture them with a digital rectal exam! On exam, typically seen in the posterior midline. If a fissure is seen in a different location, consider IBD, trauma, infection (Tuberculosis, sexually transmitted diseases), cancer. Source: UpToDate Images: Anal Fissure Anatomy What is conservative management for an anal fissure? See “ Anorectal Disease: How do I prevent anorectal disease? ” Improving bowel habits is the first-line treatment for an anal fissure. See patient handouts below. The majority of patients with an acute fissure heal with conservative management. If a fissure has been present for a long time, it is less likely to heal with conservative therapy. Sitz baths- fill a tube with water as warm as you can tolerate, and soak your bottom after every bowel movement and at least 3 times per day. Topical compounds- nitrates, calcium channel blockers→ relax muscle→ improved blood flow→ allows healing. Local anesthetics can also improve symptoms during the healing process. Avoid suppositories, Tucks pads, and Preparation H. These would be painful and won’t treat the disease. This is why diagnosis is vital. Patient Info- Anal Fissure .pdf Download PDF • 59KB Patient Info- Fiber Guide .pdf Download PDF • 68KB What is the operative management for an anal fissure? For the few patients who fail a trial of conservative therapy, surgical intervention can provide relief. Botulinum toxin (Botox) blocks neuromuscular function leading to muscle relaxation. Yes, this is the same Botox that is used to treat wrinkles. Low risk of complications. Lateral internal sphincterotomy is the treatment of choice for chronic fissures that have failed to resolve with other interventions. More successful healing compared to other interventions. Risk of incontinence (inability to control the passage of gas and stool). If incontinence occurs, the inability to control gas is more common than the inability to control liquid stool, which is more common than the inability to control solid stool. Previous Next

< Back Postoperative hypotension A 35-year-old male is in the ICU following emergency surgery for a small bowel obstruction. On arrival to the ICU, he has the following vital signs: HR 115, BP 85/40, SpO2 98. He underwent a 4-hour open lysis of adhesions. He received 2L of crystalloid and made 50 mL of dark urine, and did not require any medication to improve his blood pressure. He remains intubated and sedated. What is the differential for his hypotension? Hypovolemia- under-resuscitation relative to the insensible losses from open abdomen and likely preoperative dehydration Sepsis- bacteremia from gut translocation from small bowel obstruction, pneumonia from aspiration due to obstruction Tamponade, tension pneumothorax- did he have any intra-vascular devices placed in the OR? Pulmonary embolism- lengthy surgery, did he have appropriate mechanical prophylaxis? Cardiomyopathy The surgical team reports that he has not been tolerating a diet, or even liquids, for the previous 3 days. He received perioperative ertapenem for surgical infection prophylaxis. There was no evidence of aspiration during intubation and his admission CXR was unremarkable. He had a right internal jugular central line placed intra-operatively. He had no issues with oxygenation/ ventilation or high airway pressures intra-operatively. How can you diagnose shock and differentiate between the different potential etiologies? Physical exam- evaluation of skin turgor/ color/ temperature and mucous membranes, evaluation of fluid status (open wounds, nasogastric tube output, passive leg raise), examination of urine quality, auscultation of heart/ lungs Labs- cultures, complete blood count, lactate, liver function tests, BUN/Cr Ultrasound- gross evaluation of heart function, lung sliding to rule out pneumothorax, volume and collapsibility of the inferior vena cava Test for fluid responsiveness- based on stroke volume variation (SVV, see below), or response to passive leg raise or a fluid challenge. On exam, he is tachycardic without murmurs, lungs have equal air movement bilaterally. His nasogastric tube remains on suction with ongoing high output of gastric contents. On ultrasound, he has bilateral lung sliding. His cardiac contractility looks grossly preserved. He has normal oxygenation. His inferior vena cava is collapsible. He has a known source of infection (positive blood cultures), leukocytosis, elevated lactate, high fluid losses with evidence of fluid responsiveness. Shock: Undifferentiated Hypotension Hypotension ≠ shock. So what is shock? Inadequate perfusion to maintain end-organ function Pathophysiology: effective perfusion requires adequate cardiac output (CO). CO is the volume of blood that the heart pumps each minute, and it depends on stroke volume (SV; the volume of blood ejected with each heartbeat) and heart rate (HR; the number of heartbeats per minute). SV depends on preload (intra-vascular volume returning to the heart), myocardial contractility, and afterload (systemic vascular resistance). Shock is a disruption of preload, contractility, and/ or afterload. Signs of shock= signs of end-organ hypoperfusion Altered mental status (brain) Decreased urine output (kidney) Change in color/ temperature of extremities (skin) Abnormal liver function tests (liver) Ileus (gastrointestinal tract) Diagnosis of shock + tools for monitoring response to treatment Elevated lactate (global hypoperfusion) Ultrasound- evaluate cardiac function, evaluated IVC to assess volume status Minimally invasive cardiac monitoring (central line or arterial line)- CVP and SVV to assess volume status Invasive cardiac monitoring (pulmonary artery catheter)- cardiac output, ScVO2 (central venous oxygen saturation) Four types of shock Shock is typically categorized as hypovolemic, obstructive, cardiogenic or distributive. However, in order to link the specific category with the associated pathophysiology, I have described each state as it relates to maintaining cardiac output, as described above. Decreased preload: hypovolemic shock- low circulating blood volume→ decreased blood volume returning to the heart. Etiologies: bleeding, inadequate fluid replacement/ maintenance, high output from nasogastric tube or ostomy, insensible losses that aren't appropriately replaced (burn patients, large open wounds). Decreased preload: obstructive shock- disease process that impedes venous return to the heart (tamponade, tension pneumothorax, pulmonary embolism). Decreased contractility: cardiogenic shock- disturbance of the intrinsic function of the heart. Etiologies: heart failure, arrhythmias, valvular insufficiency, or decompensated valvular stenosis. Decreased afterload: distributive shock- dilated peripheral vasculature, sometimes known as vasoplegia. Etiologies: sepsis, anaphylaxis, neurogenic following spinal cord injury (NOTE- this is NOT the same as spinal shock), burns, trauma, pancreatitis. Neurogenic- hypotension with concurrent bradycardia. Vasoplegia is a term used to describe pathologically low systemic vascular resistance- this can be associated with post-cardiac bypass or any of the other causes mentioned here. Management of shock Treat underlying cause (see below). Restore adequate intravascular volume (aka preload). This is part of the initial treatment of hypovolemic shock, obstructive shock, and distributive shock. Fluids in the management of cardiogenic shock depend on the primary cardiac pathology. Treat hypotension/ decreased cardiac output that persists despite fluid resuscitation and treatment of the underlying cause. Septic shock- norepinephrine is the first line vasoactive medication. Monitor end-points of resuscitation (see above, Diagnosis of shock + tools for monitoring response to treatment ) Supportive care- nutrition, respiratory support, venous thromboembolism, etc. Specific Treatments Based on Etiology Hypovolemia from hemorrhage- transfusion, stop the bleeding Hypovolemia from fluid losses- replace fluid via enteral or intravenous route, as appropriate Sepsis- antibiotics, control source of infection (appendectomy, drain placement, etc). Tamponade- drainage of pericardial fluid (pericardiocentesis, pericardial window) Tension pneumothorax- release of tension physiology (needle decompression or finger thoracostomy) Cardiogenic- management of primary cardiac pathology, whether that entails treating acutely decompensated heart failure, resolving acute symptomatic arrhythmias, etc. Previous Next